Post-Conference Delivery Day
Friday, September 16 2022
9:50 am Chairs Opening Remarks
Exploring the Technologies & Devices Involved with Suprachoroidal Delivery to Prepare for the Next Generational Delivery Route
10:00 am Recent Updates on Microinjector based Suprachoroidal Gene Therapy: Potentials & Challenges
Synopsis
- SCS microinector based suprachoroidal gene delivery enables minimally invasive
office-based treatment for choroiretinal diseases - Nanoparticle based non-viral gene delivery via SC injection has potential to be a
repeatable office-based gene therapy
10:30 am Novel Suprachoroidal Delivery System Enables Rapid Distribution to the Posterior Segment & Macula
Synopsis
- Considerations for rapid and broad distribution to posterior segment when
delivering genetherapy - Innovative approach for suprachoroidal delivery using Everads’ suprachoroidal
delivery system - Perspectives of a retinal surgeon on key criteria for a suprachoroidal delivery
technology
11:00 am Morning Break
Exploring Novel Technology & Devices Involved with Ophthalmic AAV-mediated Delivery
11:30 am Looking Into Surgical & Robot-assisted Delivery of Gene Therapy Vectors
Synopsis
- Clinical methods of AAV-mediated delivery
- Gene therapy and optogenetic approaches
- Robot-assisted delivery method
12:00 pm Outlining Clinician Perspective of AAV Delivery to Understand the Most Efficacious Routes
Synopsis
- Considering patient concerns and perspectives
- Providing insight into which therapies are most efficacious with subretinal delivery
- Discussing patient outreach
12:30 pm Lunch Break & Roundtable Discussion
Understanding Surgical & Clinical Perspectives on Subretinal delivery to Understand Patient Experience & Treatment Efficacy
1:30 pm Exploring the use of Subretinal Administration for Ophthalmic Gene Therapy
Synopsis
- Summarizing the use of subretinal and suprachoroidal administration for
gene therapy - Reviewing the current and emerging technologies for subretinal administration
- Device development considerations for subretinal delivery
2:00 pm Panel Discussion– Delving into the Clinical & Surgical Challenges of Delivering Gene Therapies to the Eye Through Subretinal Pathway
Synopsis
- Presenting the clinical challenges presented by sub retinal delivery
- Discussing potential solutions to some of the major challenges
- Outlining the surgical challenges of accessing this section of the eye
- How can the technology be improved?
- Is the surgery to invasive and/or risky?