Pre-Conference Workshop Day

Tuesday September 21, 2021 | 8am - 6pm EST

Workshop A: Immune Response Mitigation Strategies for the Eye | 8am - 11am

With the eye being an immune privileged site lends ophthalmic disorders make a an optimal target for gene therapy vectors, often associated with toxic effects. However, there are still off target effects and inflammation as a result of delivery route.

Workshop will  include:

  • Understanding the biology of immune reactions of the eye
  • Discussing inflammation and its impact on trials
  • Pros & cons of subretinal delivery such as scalability
  • Evaluating different strategies being used in the clinic to manage side effects
Dominic Fishcer

Dominik Fischer
Principal Investigator &
Consultant Ophthalmic Surgeon
Oxford Eye Hospital

Workshop B: Translating Next Generation Vectors for the Eye | 11:30am - 2:30pm

To overcome delivery challenges, novel vectors are designed to improve specificity, mitigate off target effects and enhance efficacy.

Workshop will include:

  • Discovery and preclinical data for novel vectors targeting the retina
  • Exploring novel preclinical models of ophthalmic disorders and optimizing the data obtained
  • Discussing current early clinical data for novel vectors
Sanford Boye

Sanford Boye
Director of Vector Core,
Powell Gene Therapy Center
University of Florida

Chief Technology Officer
Atsena Therapeutics

Workshop C: Antisense Oligonucleotides: Evaluating Different Approaches for Ophthalmic Disorders | 11:30am - 2:30pm

Evaluating the progress with antisense oligonucleotides, cell therapy and alternative therapies for the treatment of retinal disorders to improve your understanding of the wider ophthalmology landscape.


Aniz Girach
Chief Medical Officer

Workshop D: Showcasing the Translatability of Suprachoroidal Delivery | 3pm - 6pm

With scalability challenges, the invasive nature and specialised skill set required for subretinal delivery, intravitreal delivery optimization is a priority for the field. Providing an alternative outpatient approach however is suprachoroidal delivery, which is showing promise in preclinical research.

Workshop will include:
• An explanation of suprachoroidal delivery and its advantages
• Recent preclinical and clinical data to support its implementation into gene therapy programs

thomas c

Thomas Ciulla
Vitreoretinal Medicine & Surgery, Chief
Medical Officer & Chief Development Officer
Clearside Biomedical Inc.

peter c

Peter Campochiaro
Director, Retinal Cell & Molecular
Laboratory; Professor of Ophthalmology
Johns Hopkins
University School of Medicine