Forge Biologics is a hybrid gene therapy contract manufacturing and therapeutics development company. Forge’s mission is to enable access to life changing gene therapies and help bring them from idea into reality. Forge has a 175,000 ft2 facility in Columbus, Ohio, “The Hearth,” to serve as its headquarters. The Hearth is the home of a custom-designed cGMP facility dedicated to AAV viral vector manufacturing and will host end-to-end manufacturing services to accelerate gene therapy programs from preclinical through clinical and commercial stage manufacturing. By taking a patients-first approach, Forge aims to accelerate the timelines of these transformative medicines for those who need them the most.
Our U.S. bi-coastal locations offer an extensive portfolio of preclinical research services from in vitro analyses, early discovery and proof-of-concept to discovery toxicology. Nonclinical capabilities include: pharmacokinetics, lead compound screening, proof of concept, efficacy assessment, pharmacology, mechanism of action, and early lead optimization. Biomere also provides supportive colony maintenance, backup colony support and on site room use agreements.