Arun Upadhyay

Company: Ocugen

Job title: Chief Scientific Officer

Bio:

Arun Upadhyay, PhD, Chief Scientific Officer, and Head of Research, Development and Medical, drives Ocugen’s innovation and product development. He leads science and operations, creating and implementing fit-for-purpose strategies that enable scientific and business solutions. He oversees the development of various product modalities, such as biologics, vaccines, cell and gene therapy, and regenerative medicine and is responsible for all product development activities including discovery, proof of concept, preclinical, bioanalyses, CMC, clinical, safety, medical support, and global regulatory submissions across entire R&D pipeline.

Seminars:

Endpoints for Gene Therapy Clinical Trials in Ophthalmology 9:00 am

Assessing the state-of-play with commonly used clinical endpoints in gene therapy trials: functional endpoints, structural endpoints, performance-based tests, and patient reported outcomes Comparing how the applicability of endpoints vary between those with mild loss-of-vision to profoundly blind cohorts Investigating the latest trends in endpoint development and validation (e.g., mobility mazes, microperimetry, contrast sensitivity, reading speed)…Read more

day: Development Stream 1

Striking a Balance with Ascending Dose Studies 11:20 am

Understanding the unique challenges behind achieving the correct dose for FIH studies How many doses should drug sponsors be including in ascending dose studies? Taking into consideration immunogencitiy risks when setting upper dose limitsRead more

day: Clinical Stream 3